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July 27, 1935

Les encéphalites psychosiques

JAMA. 1935;105(4):307. doi:10.1001/jama.1935.02760300067032

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This is an. elaborate and ambitious study of 120 cases, 101 fatal, of acute, subacute and chronic psychosis, without any abnormal neurologic signs or symptoms but with inflammatory and degenerative microscopic alterations in the brain. Of the 101 fatal cases, forty-four were "primary," nineteen arose in the course of a chronic psychosis, sixteen followed the puerperium, twenty followed various infections, and two were postoperative. A state of acute delirium was present in all. Nitrogen retention was such a constant feature that the term "encéphalite azotémique" is proposed. It is admitted that this is no clinical entity, that the etiology varies and that predisposition plays an important part, but claim is made for a definite and fairly uniform histologic picture. Although one may take issue with the authors on many points, they must be given credit for originality and great industry. It is a valuable contribution to the study of the

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