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In this monograph the nature of optic nerve tumors is considered in the light of observations obtained by modern neurohistologic methods. The author studied material from ten cases and in view of the probable embryologic origin of many of these tumors a study of the embryology of the optic nerves was included. In his review of the literature proper credit is given to the important works of Hudson (1912) and of Verhoeff (1922). These authors had decided that most tumors of the nerve itself should be classified as gliomas. The use of modern methods of study may be said to begin with del Rio-Hortega, who found that most optic nerve tumors were oligodendrocytomas. A table of all cases reported since the work of Hudson is included (114 cases). In studying his material the author employed besides the usual stains Holzer's glia stain and Fincher's modification of the Hortega silver and
Über die primären Tumoren des Sehnerven und der Sehnervenkreuzung. Inugural—Dissertation. JAMA. 1935;105(18):1457-1458. doi:10.1001/jama.1935.02760440067030