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November 23, 1935

BLOOD SUGAR CONCENTRATION AND THE EXTERNAL SECRETION OF THE PANCREATIC GLAND

Author Affiliations

MONTREAL

From the Department of Physiology, McGill University.

JAMA. 1935;105(21):1659-1662. doi:10.1001/jama.1935.02760470013003
Abstract

The relations between external and internal secretions of the pancreatic gland are far from being clearly understood, although some of the data seem to point to a certain connection between them.1 The data concerning the activity of the acinous tissue of the pancreas during diabetes are very contradictory. Labbé, Nepveux and Adlersberg2 and Gavrila and Paraschivesco3 reported a diminution of the enzymatic power of the pancreatic juice activated by intraduodenal introduction of ether in human diabetes. Katsch and von Friedrich4 found lower tryptic values in one out of five cases of diabetes. Jones, Castle, Mulholland and Barley5 state that in sixty-eight cases of diabetes approximately half the patients showed a diminution in the digestive power of the pancreatic juice. The poor state of nutrition of some of these patients might have played some part in this phenomenon. According to Deusch and Drost,6 clinical manifestations

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