[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.197.187.2. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Other Articles
November 23, 1935

Current Comment

JAMA. 1935;105(21):1688. doi:10.1001/jama.1935.02760470042017
Abstract

ABSORPTION FROM THE MIDDLE EAR  The fact that epithelial tissue other than that lining the lumen of the gastro-intestinal tract may be permeable to a large number of substances is well known. Vitamin D, for example, may be absorbed through the skin, and lead readily passes through pulmonary epithelium. Recently the possibility of the absorption of substances from the middle ear has been studied. In the normal subject this question would have little significance, as the middle ear, in addition to being small, is closed externally and is rather remotely open to the posterior part of the nasal cavity. In cases of infection of the middle ear, however, an absorption of toxic substances might well occur, as is indicated by the development of fever, leukocytosis and general malaise. Experimental data favoring this view have been obtained.1 Solutions of drugs that exert easily recognizable effects, such as nicotine, which raises

First Page Preview View Large
First page PDF preview
First page PDF preview
×