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March 21, 1936

AUDITORY NERVE INVOLVEMENT AFTER TETANUS ANTITOXIN: FIRST REPORTED CASE

Author Affiliations

San Francisco

From the Department of Pediatrics, Stanford University School of Medicine.

JAMA. 1936;106(12):1006-1007. doi:10.1001/jama.1936.92770120004011c
Abstract

A survey of the literature of toxic neuritis of various nerves due to the administration of tetanus antitoxin fails to reveal any report of involvement of the eighth cranial nerve. The following case is therefore of interest:

M. B., a white schoolboy, aged 14, admitted to the children's ward of Lane Hospital, Sept. 22, 1935, complained of irrationality and deafness occurring one week after the administration of tetanus antitoxin. The boy had always been in good health. About four and one-half weeks before admission he had stepped on a rusty nail in the barnyard. The wound was untreated, except for the application of iodine, and healed readily. Three weeks later he visited a physician because of twitchings in various muscle groups for one day and inability to open his jaw. Within a period of forty-eight hours he was given a total of 125,000 units of tetanus

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