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May 16, 1936

ADDISON'S DISEASE FOLLOWING ADRENAL DENERVATION

JAMA. 1936;106(20):1753. doi:10.1001/jama.1936.02770200059028

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Abstract

To the Editor:—  The comments by Drs. Hutton, Madden and Hubeny on my paper of January 25 and on the editorial in the same issue of The Journal impress me as an unconvincing clinical argument in favor of a risky empirical practice. The interpretations of the literature indicate an inadequate comprehension of the physiologic premises. Page (Am. J. Physiol.112:166 [May] 1935) obviously displaced the kidney to a superficial position because he desired to irradiate only the kidney and to avoid exposure of other organs to irradiation. Irradiation of the "adrenal region" would include the kidney, which, as Page showed, can produce hypertension. Baird, Lingley and Palmer (New England J. Med.211:952 [Nov. 22] 1934) did not claim that they damaged or attempted to damage the adrenals. Pertinent interpretation of their paper should be made from their own statements that "hypertensive patients are very suggestible, that there are

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