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This monograph summarizes the results of Koch and his pupils on the protozoic etiology of cancer. Based on the examination of 260 human cancers and on transplantable animal cancers, he concludes that cancer is due to a protozoic organism, "cellula cancrosa specifica s. parasitoia," which enters through the intestinal and female genital tracts. "All phenomena in carcinoma, as manifold as they may be, can be related easily to one cause: the presence of the parasitic cell, and they can be satisfactorily explained by this." He discusses extensively the objections which have already been made in the literature and which, in most instances, are based on the conception of the wrong interpretation of degenerated products in cancer material, as parasitic specific cells. "To the chaos of indecisive opinions and uncertain imaginations, I oppose my interpretation, which is able to relate the cytologic pictures to a uniform cause, namely, the existence of
Über die Ursache und Entstehung des Krebses: Zugleich eine Anleitung zur Erschliessung des Zellbildes bösartiger Geschwülste. JAMA. 1936;107(26):2157-2158. doi:10.1001/jama.1936.02770520059038