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February 3, 1940


JAMA. 1940;114(5):415. doi:10.1001/jama.1940.02810050035012

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In the past few years a number of pure chemical compounds simulating endocrine preparations have been developed and found to possess potency in duplicating the physiologic reactions of the endocrine glands themselves. In spite of this progress there still appears to be a profitable sale for some products prepared from animal glands which have little, if any, demonstrable activity. These so-called endocrine preparations are often sold under proprietary names. Usually they contain a few grains of one or more of desiccated ovary, testis, corpus luteum, anterior lobe or thymus. Except for the thyroid and perhaps posterior pituitary, products derived from a few grains of desiccated glandular material have never been proved to be effective in endocrine therapy.

The Council on Pharmacy and Chemistry has repeatedly exposed such obsolete preparations as worthless and has warned the medical profession against the insidious advertising and sales policies of those firms which promote them.

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