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February 24, 1940


JAMA. 1940;114(8):678. doi:10.1001/jama.1940.02810080050023

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To the Editor:—  Occasionally during the past few months I have seen communications in The Journal referring to hypersensitivity to solution of posterior pituitary. This reminds me that in November 1931 I had a case of allergic reaction from the injection of solution of posterior pituitary following the third stage of labor. Apparently the patient almost died and was saved only by the prompt administration of epinephrine.I reported this case to the manufacturer (Parke, Davis & Co.) and was advised by the chief of the research department (Dr. Kamm) that this was the first instance of which he had ever heard of allergic reaction from solution of posterior pituitary. Later, with the assistance of the American Medical Association library and Dr. Kamm, I reviewed the literature and found four or five cases reported from abroad. I then prepared a brief paper on the subject of hypersensitivity to solution of

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