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February 24, 1940


JAMA. 1940;114(8):678-679. doi:10.1001/jama.1940.02810080050024

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To the Editor.—  The editorial "Lipoid Pneumonia" (The Journal, January 20) is timely and forceful, but it falls far short of its potential value by reason of two serious omissions.Reference to Drs. P. R. Cannon and T. E. Walsh should recall at once "The Problem of Intranasal Medication," published in the Annals of Otology, Rhinology and Laryngology in September 1938. In this report was proof that the so-called mild silver proteins argyrol and neosilvol provoke pulmonary tissue reaction with consequent damage to lung tissue similar to that produced by liquid petrolatum. These products are still in common, although diminishing, use by the profession and public alike.Also, having pointed to the wrong road, had you indicated the right one you would have added utility to enlightenment. Thus, the same investigators demonstrated that isotonic saline solutions of ephedrine and related vasoconstrictors caused no reaction in pulmonary tissue. This coincides with

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