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March 9, 1940


JAMA. 1940;114(10):910. doi:10.1001/jama.1940.02810100076026

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To the Editor:—  Permit me to refer again to the question of treatment of bites by rabid animals, which was covered under Queries and Minor Notes on page 1434 of The Journal, Oct. 7, 1939.Since the Pasteur treatment is not 100 per cent effective, by reason of its inability to protect against more than one to three minimal infective doses or to develop the requisite degree of immunity in cases in which the incubation period is short, any other form of treatment which holds out any hope at all of exerting a preventive influence must be applied. The only other treatment at present available is the cautery, either actual, as in the days of Pasteur, or by nitric acid, as at present. The rationality of this procedure can be readily appreciated by a consideration of certain facts concerning virus invasions, particularly the invasion of rabies. Any one who has

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