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March 23, 1940

"DELAYED CUTANEOUS REACTION TO INTRADERMAL INJECTION OF BRUCELLERGEN"

JAMA. 1940;114(12):1099. doi:10.1001/jama.1940.02810120071030

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Abstract

To the Editor:—  In the February 10 issue of The Journal, under Clinical Notes, Suggestions and New Instruments, is an article by January and Greene entitled "Delayed Cutaneous Reaction to Intradermal Injection of Brucellergen in Brucellosis" in which the authors discuss the relative infrequency of this occurrence and quote other observers.I mentioned delayed cutaneous reaction to intradermal injection of heat-killed Brucella abortus vaccine in an article published in the New York State Journal of Medicine, Dec. 1, 1934, entitled "Undulant Fever—Difficulties in Diagnosis and Treatment—A Preliminary Report of Fifty-One Cases." This article was abstracted in The Journal, Feb. 16, 1935. In the summary of the case history of A. H. on page 3 of that article it was stated: "A skin test showed a delayed positive reaction at the end of seven days." Although I cannot find that I have discussed this subject since that date except in a

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