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April 13, 1940

The Merck Index: An Encyclopedia for the Chemist, Pharmacist, Physician, Dentist and Veterinarian Containing Useful Scientific Data and Other Information on the Physical, Chemical and Medicinal Properties, as well as the Various Uses, of Chemicals and Drugs; Also More Than 4,500 Chemical, Clinico-Chemical Reactions, Tests and Reagents; Formulas for Preparation of Culture Media, Fixatives and Staining Solutions; Useful Tables; Antidotes for Poisons; Literature References

JAMA. 1940;114(15):1487-1488. doi:10.1001/jama.1940.02810150073035

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Earlier editions are undoubtedly well known to many physicians. Those who are not familiar with it will find that the index is intended to be a practical encyclopedia for the chemist, pharmacist, physician, dentist and veterinarian. Useful information on the chemical and physical properties of some 5,900 substances, listed in many instances by their proprietary names, together with brief statements of their industrial or medicinal uses, comprises 592 pages in the new edition. The present revision appears to be the best of five compilations published since 1889. Many structural formulas illustrate the descriptions of new substances. The scheme of nomenclature employed in the list of chemicals is good, although lapses such as the use of "larocaine" for "larocaine hydrochloride" may be noted. Proprietary names of various substances are abundant in the list, although such names obviously are not exhaustively compended or cross referenced. A number of the newer proprietary pure

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