[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.205.49.6. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Other Articles
May 25, 1940

ARTERIOSCLEROSIS OF THE RENAL ARTERY ORIFICES WITH SEVERE HYPERTENSION

JAMA. 1940;114(21):2099-2101. doi:10.1001/jama.1940.62810210002011a
Abstract

In a recent discussion of experimental hypertension Goldblatt1 stated that "during the past year, in a few cases of hypertension without renal arteriosclerosis, severe sclerosis and narrowing of the orifice or lumen of the main renal arteries or the lumen of the larger extrarenal branches, obviously sufficient to cause renal ischemia, have been observed." Leiter2 reported a case of hypertension believed to be due to sclerosis of the main renal arteries (case 2). The patient's blood pressure varied from 240 to 180 systolic and from 160 to 88 diastolic; the kidneys were very small, one weighing 41, the other only 22 Gm. The glomeruli of the left kidney were hyalinized and numerous tubules were atrophied and obstructed. The main renal arterial branches had an extremely thickened, cellular and fibro-elastic intima; the internal elastica was degenerated. The medium and smaller arteries were the site of extensive degeneration of the

First Page Preview View Large
First page PDF preview
First page PDF preview
×