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June 8, 1940


JAMA. 1940;114(23):2301-2306. doi:10.1001/jama.1940.62810230004008

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II. THE USE OF IRON AND OTHER METALS  Dr. McKeen Cattell: We shall continue our general topic, treatment of disorders of the blood, with special reference to the therapeutic use of mixtures of metals and the effects of copper in relation to iron therapy. We shall hear first from Dr. Summerson, who will discuss the chemical and physiologic basis for the use of metals other than iron.

EXPERIMENTAL ASPECTS  Dr. William H. Summerson: When one speaks about the value of metals other than iron in the therapy of anemias, interest is primarily directed to copper because of the demonstration that copper is associated with iron in the formation of hemoglobin in the animal body. This was experimentally established about a decade ago, and although it was challenged at the time the facts have withstood all attempts to break them down. I think that no one seriously questions now-adays, from a

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