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June 15, 1940


JAMA. 1940;114(24):2369-2370. doi:10.1001/jama.1940.62810240002008a

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A robust Austrian smelter worker had been complaining of digestive disturbance and pain in the epigastrium at various intervals for the past few months. Three weeks before admission to the hospital he was ill at home and in bed for four days with chills, fever, malaise and coughing, all symptoms of influenza. He recovered from this illness and returned to work for four days. He came home from work on the fifth day, sick again with chills and a temperature of 105 F. by mouth. He was immediately taken to the hospital, roentgenograms were made of the chest, and he was treated for pneumonia. Sulfapyridine was given on admission; the temperature dropped and the patient was nauseated, presumably from the sulfapyridine, but his general condition improved. Figure 1 shows the course of the illness until thirty-six hours before the end. He suffered from another severe chill and fever, and twelve

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