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June 22, 1940


JAMA. 1940;114(25):2488-2489. doi:10.1001/jama.1940.02810250062020

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To the Editor:—  In the article entitled "Gallstones in Children" by Seidler and Brakeley (The Journal, May 25, p. 2082) no mention is made among the etiologic factors of the hemolytic anemias—spherocytic ictero-anemia in whites and sickle cell anemia in Negroes. While by no means common, neither are these conditions extremely rare, and they should be borne in mind whenever gallstones are encountered in children. In fact, the case reported by the authors has many features which strongly suggest the presence of sickle cell anemia. A 10 year old Negro girl with a six year history of recurrent boutsof jaundice and abdominal pain who is said to have had rheumatic fever at the age of 4 years and has experienced intervals of fever and arthralgias since and who complains now of anorexia and weakness presents the classic historical background of sickle cell anemia. The notations that she appeared to be

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