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Medical News
February 15, 1964

More Blind, Placebo Trials Of Anticoagulant Drugs Urged

JAMA. 1964;187(7):29-30. doi:10.1001/jama.1964.03060200093047

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Abstract

Drugs are very good—if you don't use them," Michael Schwartz, MD, of Glastrup Hospital in Copenhagen, told The Journal.

He reported to The International Symposium on Anticoagulants in Ischemie Heart Disease, the results of a four-year controlled study of anticoagulant therapy which was conducted in two Copenhagen hospitals. Although data indicated that there was not a definite reduction in the mortality of acute myocardial infarction following anticoagulant treatment, there was evidence that thromboembolic complications were significantly reduced in the group treated with anticoagulants.

"But this same effect—the reduction of thromboembolic complications—can be achieved in the patient by early mobilization. Why should one recommend treatment that might be dangerous, when it is possible to follow nature's way?" Schwartz asked.

"It is a curious but well established fact that discussion of anticoagulant treatment in acute myocardial infarction very often brings up severe emotions," he added. "It would be my

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