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Original Contributions
May 18, 1964

Charcot-Marie-Tooth Disease

Author Affiliations

Columbus, Ohio

From the Children's Hospital and Riverside Methodist Hospital.

JAMA. 1964;188(7):659-661. doi:10.1001/jama.1964.03060330039010

Peroneal muscular atrophy (Charcot-Marie-Tooth disease) in nine children often demonstrated characteristic, if not diagnostic, clinical features. A positive family history was highly suggestive. Biopsy specimens from two patients were of no value. Electromyelographic studies were not characteristic, but motor nerve conduction velocity studies done on five patients were significant. Recent literature was correlated with the clinical pathological and electrodiagnostic studies done on these patients.