[Skip to Content]
[Skip to Content Landing]
Original Contributions
June 1, 1964

Exposure to ParathionEffect on General Population and Asthmatics

Author Affiliations

Phoenix, Ariz; Atlanta; Tucson, Ariz

From the Toxicology Section, Technology Branch, Communicable Disease Center of the Public Health Service, US Department of Health, Education and Welfare, and Maricopa County General Hospital, Phoenix (Dr. Ganelin); Department of Microbiology and Medical Technology, University of Arizona, Tucson (Mr. Mail); and the Toxicology Section, Technology Branch, Communicable Disease Center, Atlanta (Mr. Cueto).

JAMA. 1964;188(9):807-810. doi:10.1001/jama.1964.03060350033008

There has been much lay and medical concern regarding toxic effects of insecticides on the general population. In addition to direct toxic effects, it is suspected that insecticidal application has deleterious physical effects on persons with respiratory diseases. To evaluate some of these problems, the authors have attempted to quantitate actual absorption, symptoms, and laboratory evidence of intoxication in persons with varying degrees of exposure to parathion. By means of controlled observations, the respiratory effect of application of this compound on persons with bronchial asthma was also measured. The results suggest that the effect of this chemical on the general population is negligible.