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Clinical Notes
July 20, 1964

Myositis Ossificans as a Complication of Tetanus

Author Affiliations

Jackson, Miss

From the Department of Medicine of the University of Mississippi Medical Center.

JAMA. 1964;189(3):237-239. doi:10.1001/jama.1964.03070030059022

HETEROTROPHIC CALCIFICATION, periarticular calcification, and traumatic myositis ossificans are names used as synonyms to describe the development of non-neoplastic bone in muscle following trauma. Although myositis ossificans has been reported following paralytic diseases of the central nervous system only one report of this syndrome as a complication of tetanus has been described.1 Thus the finding of myositis ossificans in two patients recovering from tetanus prompted this report.

Report of Cases 

Case 1.—  A 44-year-old Negro male was admitted to the University Medical Center on Aug 16, 1961, with tetanus. He had been in good health until Aug 6, when he received third degree burns to the lateral aspect of his left foot and leg. When he was first seen by his physician on Aug 14, the patient was not given tetanus antitoxin or toxoid. Early on the 16th he noticed "soreness between his shoulders" and "stiffness of his jaws" and

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