Observations in nine patients with clinical tetanus reveal active regression of symptoms following hyperbaric oxygen therapy. The progression of the disease was arrested and reversed. Seizures were reduced. The mental clarity and cooperation of these patients resulted in better control of respiratory problems and nutritional requirements. The need for tetanus antitoxin and tracheotomy was avoided.
Pascale LR, Wallyn RJ, Goldfein S, Gumbiner SH. Treatment of Tetanus by Hyperbaric Oxygenation. JAMA. 1964;189(6):408–410. doi:10.1001/jama.1964.03070060018003