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AUS Public Health Department experiment involving 334 nondiabetic men indicates that the oral glucose tolerance test, the most widely used test for diabetes, is apparently not reproducible.
Glen W. McDonald, MD, chief of the diabetes and arthritis program in the division of chronic diseases, said a wide range of variability was found in a series of six tests given over a period of one year to each man in the test group.
McDonald, who reported the findings to the fifth congress of the International Diabetes Federation at Toronto, said it was not the recommendation of the US Public Health Service that use of the oral glucose tolerance test be curtailed. "Rather, we hope that these results will provide greater insight into the meaning of individual tests results, and also increase the responsibility which public health workers and clinicians assume for the continued observation of suspects."
One should not assume freedom
Oral Glucose Tolerance Test May Not Be Reproducible. JAMA. 1964;189(7):29-30. doi:10.1001/jama.1964.03070070075045