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Centrally acting skeletal muscle relaxants appear to give their most beneficial results in acute muscle spasms of local origin. There is little evidence that they are of any appreciable benefit in combating chronic muscle spasm or in relieving the spasticity and contractures that accompany many neurological diseases.
This evaluation was made in a joint statement by the American Medical Association's Council on Drugs and the AMA's Committee on the Medical Aspects of Sports. It was one of several evaluations regarding the use of drugs by athletes made in a series of three joint statements. Other evaluations were as follows:
Available evidence indicates that the usefulness of orally administered enzymes to promote healing after injury by reducing the inflammation and edema of the soft tissues has not been established;
Clinical trials do not convincingly demonstrate the alleged antifatigue effects of potassium and magnesium aspartates (Spartase).
Reaffirms Stand on Amphetamines
AMA Groups Evaluate Use of Drugs in Athletes. JAMA. 1964;190(1):A49. doi:10.1001/jama.1964.03070140111049