November 9, 1964


JAMA. 1964;190(6):541. doi:10.1001/jama.1964.03070190061014

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Included in this issue of The Journal are several contributions on hemophilia, each examining a particular aspect of diagnosis and management. Plasma in large amounts (p 546) continues to be the central treatment for bleeding episodes. Fibrinogen rich in factor VIII, available for only a few years, is a much-needed and welcome addition. It has proved beneficial in complicated cases, as in the patient with hip disarticulation (p 548). Such surgery is traditionally regarded with extreme caution but should not be delayed when a clear indication exists. Tracheostomy for hemophiliacs with severe upper respiratory infection ( p 551) is but one situation where the need for emergency procedures should be anticipated well in advance. Gastric hypothermia for bleeding ulcer diathesis (p 553) assumes added importance when conventional measures fail and major surgery is considered overburdening. Complications of hemophilia are a constant threat and may be more incapacitating than the disease itself.

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