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Clinical Notes
December 28, 1964

Peritoneal Dialysis in the Management of Chronic Renal Failure

Author Affiliations

From the Department of Internal Medicine, the University of Michigan Medical Center.

JAMA. 1964;190(13):1128-1130. doi:10.1001/jama.1964.03070260040017

ALTHOUGH it had been recognized earlier that the peritoneum was a semipermeable membrane, its utilization for dialysis in the treatment of uremia was not described until 1923.1,2 Technical problems and infection prevented popular adoption of peritoneal dialysis for more than 20 years,3 although its clinical potentialities were explored.4 The development of antibiotics and plastic catheters set the stage for Maxwell5 and Doolan6 in 1959 to describe simplified procedures for conducting peritoneal dialysis.

Peritoneal dialysis has been used primarily in the treatment of acute renal failure. The treatment of chronic renal insufficiency by this method is a more recent development and experience with it is limited.7-10 The purpose of this paper is to report the use of peritoneal dialysis as an adjunct in the management of 54 patients presenting with symptoms due to chronic renal insufficiency and to attempt to assess why certain of these

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