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May 23/30, 2012

Prevention of Oral Human Papillomavirus Infection

Author Affiliations

Author Affiliation: University of Washington Center for AIDS and STD, Seattle (

JAMA. 2012;307(20):2147-2148. doi:10.1001/jama.2012.3566

To the Editor: Dr Schlecht's Editorial1 adds context to the report on the epidemiology of oral human papillomavirus (HPV) infection based on the National Health and Nutrition Examination Survey (NHANES).2 However, the subtitle undercuts some reassuring observations, such as the relatively low prevalence of oral HPV infection (6.9%) compared with anogenital infection and the 1% prevalence of oral HPV-16, the main type associated with oropharyngeal squamous cell carcinoma.2

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