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May 23/30, 2012

Prevention of Oral Human Papillomavirus Infection—Reply

Author Affiliations

Author Affiliation: Division of Infectious Diseases and HIV Medicine, Drexel University College of Medicine, Philadelphia, Pennsylvania (

JAMA. 2012;307(20):2147-2148. doi:10.1001/jama.2012.3653

In Reply: Dr Handsfield correctly points out that no data exist demonstrating that barrier protection prevents oral HPV infection during oral sex. Nevertheless, the Centers for Disease Control and Prevention encourages the use of barrier protection against sexually transmitted infections during oral sex and “with every sex act, from start to finish” in the hopes that this may prevent HPV transmission.1

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