ANAPHYLAXIS to bee sting is a rarity in older medical literature. The earliest case known is that mentioned by Mease,1 in 1836, when he recalled a letter from Dr. John R. Warren of Wardsboro, Vt., four years before. The actual stinging and its consequent fatality occurred on June 17, 1811, during Dr. Warren's childhood. Gould and Pyle,2 in 1897, summarized several early cases, including the Vermont report of 1811 and other cases. Thompson, in 1869,3 reported three fatalities from bee stings in England.
The "WPA Guide to New York State," under Manchester, mentions the grave of Timothy Ryan who was said to have been stung to death by a bee, and, in 1956, Ripley noted the gravestone of Timothy Ryan in his column, "Believe It or Not." With this limited information, a stone-by-stone search was made of the old cemeteries in or near Manchester, N.Y., about 25
Dean GA. Early Anaphylaxis to Bee Sting. JAMA. 1963;183(9):809-810. doi:10.1001/jama.1963.63700090041038