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February 23, 1963

Bronchial Asthma

Author Affiliations

Hayward, Calif.

JAMA. 1963;183(8):717. doi:10.1001/jama.1963.03700080125040

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To the Editor:  —I should like to present the essential points in my methods of treatment of asthma which have proven uniformly effective:1. Epinephrine, or one of its related drugs, by nebulization for relief of bronchospasm. This route of administration is favored over injection because of its ready availability to the patient at the onset of symptoms, when it can be expected to be most effective. Also, the much smaller amount of drug required, making for fewer side effects and palatability recommend it. Warnings as to toxic effects have little basis in fact. Recently, it has been demonstrated that alleviation of bronchospasm by nebulization, in fact, was accompanied by fall in blood pressure in hypertensive patients.2. Use of amynophylline by intravenous route. The fear of this drug in relief of bronchospasm, together with admonitions as to very slow administration, I believe to be a classic example of an

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