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July 18, 2012

Retinal Detachment and Fluoroquinolones

Author Affiliations

Letters Section Editor: Jody W. Zylke, MD, Senior Editor.

Author Affiliations: Academic Unit of Ophthalmology, University of Bristol, Bristol, United Kingdom (Dr Aristodemou; topetros@yahoo.com); and Hygeia Polyclinic, Limassol, Cyprus (Dr Stylianides).

JAMA. 2012;308(3):233. doi:10.1001/jama.2012.6618

To the Editor: The nested case-control study by Dr Etminan and colleagues1 demonstrated an association between systemic fluoroquinolone use and episodes of treatment for retinal detachment. As the authors stated, association does not imply causation. Although the adjusted rate ratios and confidence intervals were noteworthy, several important confounding factors need to be considered.

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