[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.163.92.62. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Citations 0
Letters
July 27, 2011

Opioid Overdose-Related Deaths

Author Affiliations

Author Affiliation: Tufts School of Medicine, Boston, Massachusetts (gellertreatment@hotmail.com).

JAMA. 2011;306(4):379-381. doi:10.1001/jama.2011.1036

To the Editor: Dr Bohnert and colleagues alerted the medical community to the dangers of higher opioid doses and their association with overdose death.1 Their study most likely missed cases of cardiac deaths from QTc prolongation, as the primary cause, methadone, was excluded from their investigation. However, the other major etiology of opioid-related death is ventilatory suppression via opioid-induced central sleep apnea.

First Page Preview View Large
First page PDF preview
First page PDF preview
×