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Medical News and Perspectives
April 23/30, 2003

Imaging Studies Reveal Brain Changes in Children With Bipolar Disorder

JAMA. 2003;289(16):2057. doi:10.1001/jama.289.16.2057

Bethesda, Md—New imaging research has found distinct brain changes in children diagnosed as having bipolar disorder, a first step in developing new medications to help this hard-to-treat group.

Speaking at a meeting here organized by the National Institute of Mental Health (NIMH), Melissa DelBello, MD, assistant professor of psychiatry at the University of Cincinnati College of Medicine in Ohio, said that her team has found "basic changes" in the prefrontal cortex and other brain areas of children with bipolar disorder, as compared with healthy controls.

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