[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Views 518
Citations 0
September 19, 2012

Benefits and Risks of Aspirin Use

Author Affiliations

Letters Section Editor: Jody W. Zylke, MD, Senior Editor.

Author Affiliations: Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark (Drs Lund and Toft-Sørensen) (jennifer.lund@dce.au.dk); and Department of Epidemiology, University of North Carolina, Chapel Hill (Dr Stürmer).

JAMA. 2012;308(11):1088-1089. doi:10.1001/2012.jama.10720

To the Editor: Ms De Berardis and colleagues1 reported that the use of low-dose aspirin was associated with a 55% increase in risk of major bleeding, consistent with existing evidence,2 but the incidence rates in both aspirin users and those not using aspirin were substantially higher than previously reported.2 Although it is plausible that the rates are higher in unselected patients, flaws in the study's methods may have resulted in an overestimation of bleeding rates.

First Page Preview View Large
First page PDF preview
First page PDF preview