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September 19, 2012

Telephone vs Face-to-Face Cognitive Behavioral Therapy for Depression—Reply

Author Affiliations

Letters Section Editor: Jody W. Zylke, MD, Senior Editor.

Author Affiliations: Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois (

JAMA. 2012;308(11):1090-1091. doi:10.1001/2012.jama.10729

In Reply: Drs Sarkar and Gupta suggest that posttreatment follow-up differences may have been related to differences in therapeutic alliance between the groups. Therapeutic alliance will be examined as part of preplanned secondary analyses, and we also plan to conduct detailed analyses to understand the causes of the posttreatment follow-up differences. It is possible that differences in posttreatment follow-up are artifacts resulting from better retention of patients receiving T-CBT who may be at greater risk of worsening posttreatment.

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