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October 3, 2012

Influence of Smoking on Treatment With Clopidogrel

Author Affiliations

Letters Section Editor: Jody W. Zylke, MD, Senior Editor.

Author Affiliations: Deutsches Herzzentrum München, Technische Universität München, Munich, Germany (Drs Sibbing and Kastrati) (dirk@sibbing.net); and Universitäts Herzzentrum Bad Krozingen, Bad Krozingen, Germany (Dr Hochholzer).

JAMA. 2012;308(13):1322-1324. doi:10.1001/2012.jama.11187

To the Editor: Cigarette smoking represents a major health hazard contributing significantly to cardiovascular morbidity and mortality. Although the frequency of smoking has been decreasing in many countries, a relevant number of patients with coronary artery disease are active smokers at the time of percutaneous coronary intervention (PCI). After the procedure, recommendations for patients include to receive a dual antiplatelet treatment regimen consisting of aspirin and a P2Y12 receptor inhibitor such as clopidogrel and to stop smoking.

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