Over-the-counter topical muscle and joint pain relievers may cause serious burns (http://tinyurl.com/8ok5px7), warns the US Food and Drug Administration (FDA).
The agency reviewed 43 cases of such burns in the medical literature and the agency's Adverse Events Reporting System and found that some patients using these products experienced first-, second-, and third-degree burns, even after a single application of the product. Some of these patients developed complications that required hospitalization.
Kuehn BM. Burns From Topical Pain Relievers. JAMA. 2012;308(20):2073. doi:10.1001/jama.2012.76605