Letters Section Editor: Jody W. Zylke, MD, Senior Editor.
Author Affiliations: Department of Experimental Cardiology (Dr Den Ruijter; firstname.lastname@example.org), Julius Center for Health Sciences and Primary Care (Dr Bots), University Medical Center Utrecht, Utrecht, the Netherlands.
In Reply: Carotid intima-media thickness as a tool to identify persons at highest risk for cardiovascular disease has been a subject of investigation for decades. The complex CIMT measurement can be assessed at several segments and at different angles. In addition, plaque may or may not be incorporated in the measure of thickness. In our study, we explored the added value of the mean common CIMT measurement in addition to the Framingham risk score in asymptomatic individuals.
Den Ruijter HM, Bots ML. Cardiovascular Disease Risk Prediction Measures—Reply. JAMA. 2012;308(23):2455-2456. doi:10.1001/jama.2012.65890