Letters Section Editor: Jody W. Zylke, MD, Senior Editor.
Author Affiliations: Department of Internal Medicine, University of Texas Medical Branch, Galveston (Drs Calhoun and Ameredes) (firstname.lastname@example.org); and Department of Medicine, University of California, San Francisco (Dr Boushey).
In Reply: Drs Sterk and Sont authored a seminal study on asthma treatment algorithms,1 but the purpose of BASALT was quite different from their work. Our purpose was to assess the utility of symptoms as a guide to controller therapy, compared with their purpose to assess the added value of another biomarker (ie, bronchial hyperresponsiveness) to asthma control.
Calhoun WJ, Boushey HA, Ameredes BT, Asthma Clinical Research Network BASALT Trial Investigators FT. Strategies for Tailoring Asthma Treatment in Adults—Reply. JAMA. 2013;309(2):136-137. doi:10.1001/jama.2012.73385