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January 9, 2013

Strategies for Tailoring Asthma Treatment in Adults—Reply

William J. Calhoun, MD; Homer A. Boushey, MD; Bill T. Ameredes, PhD; et al for the Asthma Clinical Research Network BASALT Trial Investigators
Author Affiliations

Letters Section Editor: Jody W. Zylke, MD, Senior Editor.

Author Affiliations: Department of Internal Medicine, University of Texas Medical Branch, Galveston (Drs Calhoun and Ameredes) (william.calhoun@utmb.edu); and Department of Medicine, University of California, San Francisco (Dr Boushey).

JAMA. 2013;309(2):136-137. doi:10.1001/jama.2012.73385

In Reply: Drs Sterk and Sont authored a seminal study on asthma treatment algorithms,1 but the purpose of BASALT was quite different from their work. Our purpose was to assess the utility of symptoms as a guide to controller therapy, compared with their purpose to assess the added value of another biomarker (ie, bronchial hyperresponsiveness) to asthma control.

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