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Lab Reports
March 6, 2013

How TB Bacteria Hide Out

JAMA. 2013;309(9):865-865. doi:10.1001/jama.2013.1314

Mycobacterium tuberculosis bacteria can maintain long-term viability inside bone marrow stem cells grown in vitro, hidden from the immune system, according to findings of an international team studying a mouse model of dormant tuberculosis (TB) infection (Das B et al. Sci Transl Med. 2013;5[170]:170ra13).

The investigators also detected viable M tuberculosis in a mesenchymal subpopulation of bone marrow stem cells isolated from individuals who had successfully completed months of TB drug treatment.

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