Author Affiliations: American College of Cardiology Foundation, Washington, DC (Drs Zoghbi and Holmes); Mayo Clinic Foundation, Rochester, Minnesota (Dr Holmes); and The Methodist DeBakey Heart and Vascular Center, Houston, Texas (Dr Zoghbi).
The past 30 years have seen major shifts in cardiovascular science and medicine. In the United States, mortality due to cardiovascular disease (CVD) has declined by more than 60% as a result of new therapeutic approaches, including the introduction of statins, better anticoagulants, angiotensin-converting enzyme inhibitors, devices such as implantable cardioverter-defibrillators, and—perhaps foremost—the application of evidence-based scientific guidelines.1 There is every reason to believe further progress will occur during the next few decades, although some signs suggest that the current emphasis may change.
Zoghbi WA, Holmes DR. Improving Cardiovascular HealthA Balance Between Discovery and Delivery. JAMA. 2013;309(11):1117-1118. doi:10.1001/jama.2013.2416