Annual mass treatment with ivermectin to prevent the parasitic disease onchocerciasis, also called river blindness, has led to cost-effective health improvements in sub-Saharan Africa (Coffeng LE. PLoS Negl Trop Dis. 2013;7:e2032).
Researchers used a microsimulation model to estimate the health effect and cost of the African Programme for Onchocerciasis Control, a morbidity control program implemented by the World Health Organization in 1995 and set to run through 2015, when participating countries are expected to coordinate control measures themselves.
Friedrich MJ. Control of River Blindness. JAMA. 2013;309(11):1101. doi:10.1001/jama.2013.2398