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Health Agencies Update
March 27, 2013

Glucose During Pregnancy

JAMA. 2013;309(12):1220. doi:10.1001/jama.2013.2718

After recent findings identified added risks for women with elevated blood glucose levels during pregnancy, a follow-up study will investigate whether these women are at greater risk of developing diabetes later in life or of having overweight children.

The original Hyperglycemia and Adverse Pregnancy Outcomes (HAPO) study, launched in 2000, examined more than 23 000 mother-child pairs and found that women who had elevated blood glucose levels during pregnancy but who did not meet the criteria for gestational diabetes delivered heavier babies with more body fat. The women with elevated blood glucose levels were also more likely to deliver by cesarean. Now the researchers will seek to follow up 7000 of the original mother-child pairs to determine if mothers with elevated glucose levels are at increased risk of developing diabetes and whether their children, now 8 to 12 years old, have excess body fat. The researchers said in a statement they hope to determine whether lowering blood glucose level cutoff points during pregnancy will help predict later health outcomes for mother and child.

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