[Skip to Content]
[Skip to Content Landing]
April 10, 2013

The Indispensable Role of Professional Judgment in Genomic Medicine

Author Affiliations

Author Affiliations: Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, Texas (Drs McGuire and McCullough); and Department of Genetics, University of North Carolina School of Medicine, Chapel Hill (Dr Evans).

JAMA. 2013;309(14):1465-1466. doi:10.1001/jama.2013.1438

Whole-genome sequencing and whole-exome sequencing (WGS/WES) have become increasingly affordable and accessible to individuals. There are currently 3 main pathways through which a person can receive WGS/WES: as a research participant in a genomic study; through a direct-to-consumer personal genome company; or as part of clinical care. In the research context, the extent to which findings from WGS/WES are communicated to study participants and used to inform their clinical care is a topic of much debate, but guidelines suggest that investigators may have an obligation to offer at least some results to study participants.1

First Page Preview View Large
First page PDF preview
First page PDF preview