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From JAMA's Daily News Site
May 15, 2013

Selections From News@JAMA and JAMA Forum

JAMA. 2013;309(19):1983. doi:10.1001/jama.2013.5120

A daily dose of allergens under the tongue appears to be effective in desensitizing patients with allergic rhinitis or asthma to respiratory allergens.

In a recent review article, researchers found moderate evidence supporting the efficacy of sublingual therapy. In 8 of 13 studies they evaluated, patients with asthma who were treated with this approach had a 40% or greater improvement in symptoms compared with a control or alternate therapy group. Evidence of efficacy for allergic rhinitis was moderate: 9 of 36 studies showed a 40% or more improvement in symptoms. Although common in Europe, sublingual therapy isn't approved by the US Food and Drug Administration.

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