Changes in breastfeeding routines during the time of weaning influence the concentration of HIV in breast milk, according to findings from a randomized clinical trial in Zambia (Kuhn L et al. Sci Transl Med. 2013;5:181ra51).
Researchers from the United States and Zambia tested different breastfeeding routines during a 24-month period in 958 women infected with HIV. All women were counseled to breastfeed for 4 months, at which point half were encouraged to wean abruptly while the other half continued breastfeeding as long as they chose to do so. HIV-1 RNA and DNA were measured at 4 and 4.5 months.
Friedrich MJ. Weaning Affects HIV Levels in Breast Milk. JAMA. 2013;309(23):2430. doi:10.1001/jama.2013.7390