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Lab Reports
July 3, 2013

Brain Protein May Suggest New Epilepsy Treatment Strategy

JAMA. 2013;310(1):22. doi:10.1001/jama.2013.7873

A protein produced within the brain acts like antiepileptic drugs, report researchers from Stanford University School of Medicine in Stanford, California (Christian CA et al. Neuron. doi:10.1016/j.neuron.2013.04.026 [published online May 30, 2013]). In addition to being an intracellular transporter of a metabolite called acyl-CoA, the protein, diazepam binding inhibitor (DBI), binds to receptors on nerve cells that are responsive to the inhibitory neurotransmitter γ-aminobutyric acid type A (GABAA).

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