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September 28, 2011

Statin Therapy Dose and Risk of New-Onset Diabetes

Author Affiliations

Letters Section Editor: Jody W. Zylke, MD, Senior Editor.

Author Affiliation: Division of Cardiology, Johns Hopkins University, Baltimore, Maryland (

JAMA. 2011;306(12):1325-1326. doi:10.1001/jama.2011.1354

To the Editor: Dr Preiss and colleagues1 demonstrated that intensive-dose statin therapy was associated with an increased risk of incident diabetes compared with moderate-dose therapy in a meta-analysis of randomized trials. These results add to their prior meta-analysis that demonstrated an association between randomization to statins vs control treatment and the development of diabetes.2