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Comment & Response
July 10, 2013

Aldosterone Inhibition in Patients With Heart Failure With Preserved Ejection Fraction

Author Affiliations
  • 1Karolinska Institutet, Stockholm, Sweden
JAMA. 2013;310(2):205. doi:10.1001/jama.2013.7967

To the Editor The Aldo-DHF trial1 (similar to other trials in HF with preserved EF2,3) failed to demonstrate a benefit from neurohormonal antagonism. We are concerned about the inclusion criteria and power of the study.

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