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Comment & Response
July 10, 2013

Myocardial Thinning in Patients With Coronary Artery Disease—Reply

Author Affiliations
  • 1Methodist DeBakey Heart and Vascular Center, Houston, Texas
  • 2Duke Cardiovascular Magnetic Resonance Center, Duke University Medical Center, Durham, North Carolina
JAMA. 2013;310(2):207-208. doi:10.1001/jama.2013.7936

In Reply We agree that following an acute MI, infarct healing and wall thinning may not be completed for weeks to months. In our population, patients with an acute MI within 2 weeks of potential enrollment were excluded, and 71% of enrolled patients had a history of prior MI.

We do not have data concerning the time between the diagnosis of MI and the performance of delayed-enhancement CMR imaging. However, if our population had included a sizable fraction of patients with relatively recent MI, the reported prevalence of 19% with regional wall thinning may represent an underestimate compared with a population in which all patients with an MI within the last 6 months were excluded.

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